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Mechanism of vascular endothelial growth factor on the prevention of restenosis after angioplasty

Qigong LIU, Honglian ZHOU, Yan ZENG, Shan YE, Jiani LIU, Zaiying LU

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 177-180 doi: 10.1007/s11684-009-0021-x

Abstract: To evaluate the mechanism of vascular endothelial growth factor (VEGF) on the prevention of restenosisangioplasty, the recombinant adenovirus vector containing hVEGF cDNA was constructed and transfected into vascularThen, the VSMC and human umbilical vein endothelial cells (HUVEC) were divided into control group, H

Keywords： vascular endothelial growth factors     restenosis     reactive oxygen species     endothelial cells     vascular smoothmuscle cell    

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Role of nitric oxide in biological effects of vascular endothelial growth factor

Qigong LIU M D , Yan ZENG , Jiani LIU , Shan YE , Yongdong LI , Zaiying LU M D ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 284-286 doi: 10.1007/s11684-009-0062-1

Abstract: To evaluate the role of nitric oxide in the biological effects of vascular endothelial growth factor(VEGF) and the possible mechanism of VEGF, the cultured vascular endothelial cells of rabbit aorta wereThe absorbance () value of vascular endothelial cells and the levels of prostaglandin (PGI), endothelin-1 (ET-1) and von Willebrand factor (vWF) in the supernatant were observed by water-soluble tetrazoliumendothelial cells by VEGF.

Keywords： vascular endothelial growth factor     nitric oxide     N-nitro-L-arginine methyl ester     vascular endothelial    

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Lymphatic metastasis is related to the epithelial-mesenchymal transition and expressions of VEGF, MMP-9, and COX-2 in breast cancer

Lihui WANG, Lianhong LI, Shen LV, Shujun FAN, Li ZHAN, Bo WANG, Zhong ZHANG

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 164-170 doi: 10.1007/s11684-009-0038-1

Abstract: The expressions of E-cadherin (E-Cad), N-cadherin (N-Cad), vascular endothelial cell growth factor (VEGF

Keywords： epithelial-mesenchymal transition     vascular endothelial cell growth factor     matrix metalloproteinase-9    

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Changes in Lipoprotein Lipase in the Heart Following Diabetes Onset Review

Chae Syng Lee, Yajie Zhai, Brian Rodrigues

Engineering 2023, Volume 20, Issue 1,   Pages 19-25 doi: 10.1016/j.eng.2022.06.013

Abstract: To then move LPL to the endothelial cell (EC) lumen, glycosylphosphatidylinositol-anchored high-densitylipoprotein-binding protein 1 (GPIHBP1) attaches to interstitial LPL and transfers it to the vascularlipid metabolite accumulation, along with augmented FA oxidation and thus oxidative stress, leads to cellThis coincides with the loss of a cardioprotective growth factor—namely, vascular endothelial growthfactor B (VEGFB).

Keywords： Cardiac metabolism     Lipoprotein lipase     Heparanase     Vascular endothelial growth factor     Diabetic cardiomyopathy    

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Expression of PC-cell-derived growth factor in breast cancer

Haiping SONG MD, Lan SHI MD, Chunping LIU MD, Tao HUANG MD,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 426-430 doi: 10.1007/s11684-009-0085-7

Abstract: This study is mainly aimed at evaluating the expression of PC-cell-derived growth factor (PCDGF) in breast

Keywords： PC-cell-derived growth factor     breast neoplasms     clinical markers    

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Involvement of p38 mitogen-activated protein kinase in the regulation of platelet-derived growth factor-induced cell migration

GONG Xiaowei, WEI Jie, LI Yusheng, CHENG Weiwei, DENG Peng, JIANG Yong

Frontiers of Medicine 2007, Volume 1, Issue 3,   Pages 248-252 doi: 10.1007/s11684-007-0047-x

Abstract: The aim of this study was to investigate the role of p38 mitogen-activated protein kinase (MAPK) in cellmigration induced by platelet-derived growth factor (PDGF).A Transwell cell migration system was used to determine the effects of PDGF treatment on the migrationand the influence of deficiency on this process in a gene knockout (p38) mouse embryonic fibroblast cellFurthermore, the PDGF-induced cell migration was significantly blocked in gene knockout (p38) mouse

Keywords： control     stimulation     mitogen-activated     growth factor     process    

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lncR-GAS5 upregulates the splicing factor to impair endothelial autophagy, leading to atherogenesis

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 317-329 doi: 10.1007/s11684-022-0931-4

Abstract: Here, we investigated the role of the lncRNA growth arrest-specific 5 (lncR-GAS5) in atherogenesis.decreased LC3II/LC3I protein ratio and an elevated P62 level in lncR-GAS5-overexpressing human aortic endothelialMoreover, serine/arginine-rich splicing factor 10 (SRSF10) knockdown increased the LC3II/LC3IMechanistically, lncR-GAS5 regulated the downstream splicing factor SRSF10 to impair autophagyIn conclusion, lncR-GAS5 overexpression arrested endothelial autophagy through the miR-193-5p/SRSF10

Keywords： lncR-GAS5     miR-193-5p     splicing factor SRSF10     autophagy     atherogenesis    

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Endogenous tissue factor pathway inhibitor in vascular smooth muscle cells inhibits arterial thrombosis

Jichun Yang, Kaiyue Jin, Jiajun Xiao, Jing Ma, Duan Ma

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 403-409 doi: 10.1007/s11684-017-0522-y

Abstract:

Tissue factor pathway inhibitor (TFPI) is the main inhibitor of tissue factor-mediated coagulationTFPI is expressed by endothelial and smooth muscle cells in the vasculature.However, the role of endogenous TFPI in vascular smooth muscle cells (VSMCs) in thrombosis and vascularPlasma TFPI concentration was also detected in the TFPITie2 (mice deleted TFPI in endothelial

Keywords： arterial thrombosis     conditional knockout mice     tissue factor pathway inhibitor     vascular smooth muscle    

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Study on the action of resistin-induced human umbilical vein endothelial cell dysfunction

LI Zhizhen, LI Fangping, YAN Li, LI Feng, LI Yan, CHENG Hua, FU Zuzhi

Frontiers of Medicine 2007, Volume 1, Issue 2,   Pages 196-199 doi: 10.1007/s11684-007-0037-z

Abstract: The aim of this paper was to investigate the effects of resistin on human umbilical vein endothelial

Keywords： endothelial     resistin stimulation     Incubation     pathogenesis     dysfunction    

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Relative expression of PTTG and bFGF in oral squamous cell carcinoma and Tca8113

Yumei DING BM , Lili CHEN MD , Bo CHENG PhD , Handong ZHANG MM ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 357-362 doi: 10.1007/s11684-009-0046-1

Abstract: was to investigate the expression of pituitary tumor transforming gene (PTTG) and basic fibroblast growthfactor (bFGF) in oral squamous cell carcinoma (OSCC) and tongue cancer cell line Tca8113, as well as

Keywords： carcinoma     squamous cell     pituitary tumor transforming gene (PTTG) protein     basic fibroblast growth factor    

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The relationship between platelet-derived growth factor expression and angiogenesis/lymphangiogenesis

Guocheng LIU MD, Shouhua YANG MD, Zehua WANG MD,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 447-451 doi: 10.1007/s11684-009-0082-x

Abstract: This paper is aimed to examine if changes in platelet-derived growth factor (PDGF) expression at different

Keywords： cervical cancer     lymphatic vessel density     blood vessel density     platelet-derived growth factor    

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Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiology

Huating Li, Jing Zhang, Weiping Jia

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 25-30 doi: 10.1007/s11684-013-0244-8

Abstract:

Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor family.It actually functions as endocrine hormones but does not regulate cell growth and differentiation.Moreover, FGF21 also plays important roles in some physiological processes, such as fasting and feeding, growth

Keywords： FGF21     metabolism     pharmacology     physiology     clinical relevance    

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Current advances for bone regeneration based on tissue engineering strategies

Rui Shi, Yuelong Huang, Chi Ma, Chengai Wu, Wei Tian

Frontiers of Medicine 2019, Volume 13, Issue 2,   Pages 160-188 doi: 10.1007/s11684-018-0629-9

Abstract: such as weaker osteogenic differentiation, inadequate vascularization of scaffolds, and inefficient growthfactor delivery.We describe the cell sources, biology of seed cells, growth factors, vascular development, and the interactions

Keywords： bone tissue engineering     stem cell     bone scaffold     growth factor     bone regeneration    

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sulfate promotes the formation of atherosclerotic lesions and induces plaque instability by targeting vascular

Hui Han,Yanjia Chen,Zhengbin Zhu,Xiuxiu Su,Jingwei Ni,Run Du,Ruiyan Zhang,Wei Jin

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 320-329 doi: 10.1007/s11684-016-0463-x

Abstract: Rat aortic vascular smooth muscle cells (VSMCs) were treated with phosphate buffer solution or 500 µ

Keywords： p-cresyl sulfate     atherosclerosis     plaque stability     vascular smooth muscle cell    

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An investigation on prevalent strategies for XFEM-based numerical modeling of crack growth in porous

Frontiers of Structural and Civil Engineering 2021, Volume 15, Issue 4,   Pages 914-936 doi: 10.1007/s11709-021-0750-8

Abstract: Crack growth modeling has always been one of the major challenges in fracture mechanics.Finally, the crack growth is modeled in a natural porous media (Fontainebleau sandstone).Both strategies are reliable and highly accurate in calculating the stress intensity factor, but thetests showed that the second strategy is a more accurate strategy in predicting the preferred crack growth

Keywords： numerical modeling     extended finite element method     porous media     crack growth     stress intensity factor    

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Title Author Date Type Operation

Mechanism of vascular endothelial growth factor on the prevention of restenosis after angioplasty

Qigong LIU, Honglian ZHOU, Yan ZENG, Shan YE, Jiani LIU, Zaiying LU

Journal Article

Role of nitric oxide in biological effects of vascular endothelial growth factor

Qigong LIU M D , Yan ZENG , Jiani LIU , Shan YE , Yongdong LI , Zaiying LU M D ,

Journal Article

Lymphatic metastasis is related to the epithelial-mesenchymal transition and expressions of VEGF, MMP-9, and COX-2 in breast cancer

Lihui WANG, Lianhong LI, Shen LV, Shujun FAN, Li ZHAN, Bo WANG, Zhong ZHANG

Journal Article

Changes in Lipoprotein Lipase in the Heart Following Diabetes Onset

Chae Syng Lee, Yajie Zhai, Brian Rodrigues

Journal Article

Expression of PC-cell-derived growth factor in breast cancer

Haiping SONG MD, Lan SHI MD, Chunping LIU MD, Tao HUANG MD,

Journal Article

Involvement of p38 mitogen-activated protein kinase in the regulation of platelet-derived growth factor-induced cell migration

GONG Xiaowei, WEI Jie, LI Yusheng, CHENG Weiwei, DENG Peng, JIANG Yong

Journal Article

lncR-GAS5 upregulates the splicing factor to impair endothelial autophagy, leading to atherogenesis

Journal Article

Endogenous tissue factor pathway inhibitor in vascular smooth muscle cells inhibits arterial thrombosis

Jichun Yang, Kaiyue Jin, Jiajun Xiao, Jing Ma, Duan Ma

Journal Article

Study on the action of resistin-induced human umbilical vein endothelial cell dysfunction

LI Zhizhen, LI Fangping, YAN Li, LI Feng, LI Yan, CHENG Hua, FU Zuzhi

Journal Article

Relative expression of PTTG and bFGF in oral squamous cell carcinoma and Tca8113

Yumei DING BM , Lili CHEN MD , Bo CHENG PhD , Handong ZHANG MM ,

Journal Article

The relationship between platelet-derived growth factor expression and angiogenesis/lymphangiogenesis

Guocheng LIU MD, Shouhua YANG MD, Zehua WANG MD,

Journal Article

Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiology

Huating Li, Jing Zhang, Weiping Jia

Journal Article

Current advances for bone regeneration based on tissue engineering strategies

Rui Shi, Yuelong Huang, Chi Ma, Chengai Wu, Wei Tian

Journal Article

sulfate promotes the formation of atherosclerotic lesions and induces plaque instability by targeting vascular

Hui Han,Yanjia Chen,Zhengbin Zhu,Xiuxiu Su,Jingwei Ni,Run Du,Ruiyan Zhang,Wei Jin

Journal Article

An investigation on prevalent strategies for XFEM-based numerical modeling of crack growth in porous

Journal Article